Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
نویسندگان
چکیده
منابع مشابه
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
activity as well as biological function in vivo (Gu et al., By developing site-specific acetylated p53 antibod-ies, CBP/p300 mediated acetylation of p53 was further confirmed in vivo by a number of studies (reviewed in Summary Appella and Anderson, 2000). Significantly, the steady-state levels of acetylated p53 are stimulated in response The NAD-dependent histone deacetylation of Sir2 con-to va...
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ژورنال
عنوان ژورنال: Cell
سال: 2001
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(01)00524-4